Marfan Syndrome and Related Disorders
Marfan syndrome is an inherited disorder of the connective tissue (fibers that provide the framework and support for the body) that is estimated to occur in at least 1 in 5,000 persons. It is seen in all races and ethnic groups, and can appear at any age. Marfan syndrome is characterized by multiple abnormalities in the connective tissue primarily affecting the skeleton system (bones and ligaments), the cardiovascular system (heart and blood vessels), the eyes, the lungs, and the skin.
Cardiovascular abnormalities associated with Marfan syndrome are by far the most serious abnormalities, potentially causing life-threatening situations and death. Cardiovascular abnormalities associated with Marfan syndrome include aneurysm (enlargement), dissection (tear within the inner wall), or rupture of the aorta and/or aortic root, as well as mitral valve disease. Cardiac surgeons, S. Chris Malaisrie, MD and Patrick M. McCarthy, MD, have championed and offer the most advanced surgical techniques such as valve-sparing aortic root surgery and mitral valve repair to correct these cardiovascular abnormalities.
The Marfan Syndrome and Related Disorders Clinic understands that with focused and appropriate medical and surgical intervention, Marfan syndrome patients with cardiovascular abnormalities can expect to achieve longevity comparable to people without connective tissue disorders.
For more information regarding Marfan syndrome and related disorders, please contact the Bluhm Cardiovascular Institute at 312-NM-HEART (664-3278) or request a first time appointment online.
In addition, the most credible source of information about Marfan syndrome is the National Marfan Foundation (NMF). Please visit the NMF Web site.